The Louisiana Art & Science Museum’s annual exhibition program is generously sponsored by Entergy.

Several exhibitions are also generously supported by Cary Saurage through the Alma Lee, Norman, and Cary Saurage Fund of the Baton Rouge Area Foundation; the Louisiana Division of the Arts, Office of Cultural Development, Department of Culture, Recreation and Tourism, in cooperation with the Louisiana State Arts Council, as administered by the Arts Council of Greater Baton Rouge; funding provided by the National Endowment for the Arts; and the 2021 Rebirth grant, administered by the Louisiana Endowment for the Humanities (LEH) and provided by the National Endowment for the Humanities (NEH) as part of the American Rescue Plan (ARP) and the NEH Sustaining the Humanities through the American Rescue Plan (SHARP) initiative.

The Louisiana Art & Science Museum has also received a 2023 Louisiana Cultural Care Fund Grant, which provides generous general operating support related to LASM's exhibitions, with funding provided by the State of Louisiana and administered by the Louisiana Endowment of the Humanities.